Pogonomyrmex sp., probably P. californicus – harvester ants; were used as a hallucinogen and medicine by southern California Indians (Blackburn 1976, Groark 1996).
This genus of ants has the greatest mammalian toxicity known of any arthropod (Schmidt and Blum 1978, Groark 1996), with an intravenous LD50 of 0.3-1.1 mg/kg (Schmidt and Blum 1978, Groark 1996).
For use as a ritualistic hallucinogen, in the context of a “vision quest” of Indian youth, harvester ants were eaten after three days of fasting from food, water, and sex and not contacting blood (Groark 1996). In the daytime at an isolated location fully exposed to the elements, an experienced elder administrator, the ant doctor, would lay the youth on their back and feed him, somewhat forcibly, balls of moistened eagle down with about 5 ants inside each (Blackburn 1976, Groark 1996). The dose was regulated, from dozens to ninety or so balls, and the ant feeding stopped when the eyes of the youth turned red and he became lethargic and refused more (Groark 1996). The ant doctor then acts as if they are leaving momentarily, then sneaks up behind and pokes the ribs hard to startle the youth, provoking the ants to all sting his insides at once, causing the youth to pass out (Groark 1996). In most cases, the ants were eaten just once, but in some cases, when the youth awoke several hours later, he would be asked if they can take more ants, repeating the process if able for 2-4 days (Groark 1996).
In the near-death state, the youth would have visions, wherein he would obtain spirits of animals, dream-helpers, to help him in certain abilities in life (Groark 1996). For 4 days afterward, the youth must stay alone and he and the ant doctor must not speak to anyone (Groark 1996). To obtain shamanistic powers, the ants would be eaten in a similar mannar every summer until the powers were obtained (Groark 1996). The ants were also eaten similarly for a variety of ailments, from paralysis to severe colds (Groark 1996).
Blackburn, T. 1976. A query regarding the possible hallucinogenic effects of ant ingestion in south-central California. The Journal of California Anthropology 3(2): 78-81.
Groark, K. P. 1996. Ritual and therapeutic use of “hallucinogenic” harvester ants (Pogonomyrmex) in native south-central California. Journal of Ethnobiology 16(1): 1-29.
Schmidt, J. O. and M. S. Blum. 1978. A harvester ant venom: chemistry and pharmacology. Science, New Series 200(4345): 1064-1066).